Figure 2
Keywords: Histopathology-image, Pathology, Reactive perforating collagenosis
The low power view of perforating collagenosis shows an invaginating epidermal process (Figure 1). There is hyperkeratosis overlying a cup shaped depression or invagination in the epidermis. There is prominent epidermal hyperplasia, which encompasses a central basophilic plug of keratin, collagen and inflammatory debris (Figure 2). On careful sectioning, this is continuous with altered collagen in the underlying dermis, which is being expelled by the process of transepidermal elimination. Within the epidermal plug bright eosinophilic altered collagen fibres can be seen (Figures 3 and 4).
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