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Necrosis induced by warfarin in an individual with protein C deficiency. The breasts and thighs are more common sites
Keywords: Collapsed bullae, Coumarin congener, Crust, Erythematous halo, Leg, Protein C deficiency, Retiform purpura, Sensitive-image, Severe ulceration, Skin necrosis, Skin sloughing, Warfarin anticoagulant, Yellow excudate
Warfarin is an anticoagulant medicine (blood thinner). Warfarin-induced skin necrosis refers to a rare condition in which there is paradoxical blood clotting. Blood clots block the blood vessels and cause necrosis, where an area of skin is destroyed. Warfarin-induced skin necrosis affects one in every 10,000 patients prescribed warfarin.
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Source: Dr Ian Coulson