Close-up demonstrating the swelling on the leg due to pretibial myxoedema (PTM-patient1)
Keywords: Female, Hyperpigmentation, Infiltrative dermopathy, Localised myxoedema, Medium strength corticosteroid, Post RAI treatment, Postinflammatory hyperpigmentation, Regression post cordran tape treatment, Thyroid dermopathy
Pretibial myxoedema is a form of diffuse mucinosis in which there is an accumulation of excess glycosaminoglycans in the dermis and subcutis of the skin. Glycosaminoglycans, also called mucopolysaccharides, are complex carbohydrates that are important for tissue hydration and lubrication. The main glycosaminoglycan in pretibial myxoedema is hyaluronic acid, which is made by cells called fibroblasts.
© Dr Lawrence Meyerson
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Source: dermnetnz.org
