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Gross elephantiasic plaques of myxoedema on the leg

Orange-red nodular plaque of pretibial myxoedema - the patient had ophthalmic Graves' disease treated with radioiodine (PTM-patient1)

Orange-red nodular plaque of pretibial myxoedema - the patient had ophthalmic Graves' disease treated with radioiodine (PTM-patient1)

Close-up demonstrating the swelling on the leg due to pretibial myxoedema (PTM-patient1)

Pretibial myxoedema just above the ankle - the patient had a past history of thyrotoxicosis (PTM-patient1)

Pretibial myxoedema showing yellow-brown patches on the shin

Diffuse soft swelling overlying the tibia in pretibial myxoedema (PTM-patient2)

Diffuse soft swelling overlying the tibia in pretibial myxoedema (PTM-patient2)

Diffuse soft swelling overlying the tibia in pretibial myxoedema (PTM-patient3)

Bilateral orange-red swellings on the lower leg in pretibial myxoedema (PTM-patient3)

Red-brown patches on the shin - biopsy showed mucin accumulation confirming pretibial myxoedema

Close-up of a patch of early pretibial myxoedema (PTM-patient4)

Subtle early pretibial myxoedema - palpation showed mild induration (PTM-patient4)

Pale nodules of pretibial myxoedema in skin of colour on the lower leg (PTM-patient5)

Pale nodules of pretibial myxoedema in skin of colour (PTM-patient5)

Pale nodules of pretibial myxoedema in skin of colour on the lower leg (PTM-patient5)

Mucin accumulation around the ankles causing nodules and plaques due to pretibial myxoedema (PTM-patient6)

Mucin accumulation around the ankles causing nodules and plaques due to pretibial myxoedema (PTM-patient6)

Bilateral infiltrative plaques on the lower shins and ankle due to mucin accumulation in pretibial myxoedema (PTM-patient6)

A close-up view of nodular pretibial myxoedema (PTM-patient6)

Orange-red plaques around the ankles in pretibial myxoedema (PTM-patient7)

Orange-red plaques around the ankles in pretibial myxoedema (PTM-patient7)












