Squamous intraepithelial lesion

Author: Chief Editor: Dr Amanda Oakley, Dermatologist, Hamilton, New Zealand, 2015.

Synonyms:

SIL

Categories:

Age site specific, Viral infection, Tumour

Subcategories:

LSIL, HSIL, Low grade SIL, High grade SIL, Human papillomavirus, Anogenital HPV, Superficial noninvasive neoplasm, SCC-in-situ, VIN, PIN, AIN, Bowenoid papulosis

ICD-10:

N90.0, N90.1, N90.3, D07.1, D01.3, K62.82, R85.81, R85.82, D07.4, B97.7

ICD-11:

2E61.2, 2F33.0, 2E64.2, 2E67.40, 1A95.1, 1A9Y

SNOMED CT:

24253004, 112662005, 22725004, 767544007, 20365006, 402913004, 9482002

What is squamous intraepithelial lesion?

Squamous intraepithelial lesion (SIL) is the current preferred terminology to use when referring to superficial non-invasive mucosal neoplasias of the anogenital region associated with human papillomavirus (HPV) infection. The tumours can be classified as high grade (HSIL) or low grade (LSIL).

SIL is also commonly known by older names relating to the specific site of the lesion, as squamous cell carcinoma in situ, or as Bowen disease.

Vulval intraepithelial neoplasia or VIN
Penile intraepithelial neoplasia or PIN (also called erythroplasia of Querat)
Anal intraepithelial neoplasia or AIN
Bowenoid papulosis

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Related information

On DermNet NZ

Other websites

VULVAR SQUAMOUS INTRAEPITHELIAL LESIONS —ISSVD (PDF)