Neonatal cephalic pustulosis is a variant of neonatal acne (see acne in children). It is a pustular eruption arising on the face and/or scalp of newborn babies, often during the third week. Unlike true neonatal acne, there are no comedones (blackheads, whiteheads).
Neonatal cephalic pustulosis is related to malassezia colonisation, which may be found on mycology (microscopy and culture) of smears from facial pustules.
Neonatal cephalic pustulosis generally resolves without treatment. However, if the appearance is unsightly, a topical antifungal such as ketoconazole cream can be used safely and may be helpful.
