Figure 5
Keywords: Pilomatricoma, Histopathology-image, Pathology
At low power the histological pattern seen in pilomatricoma is of a well-circumscribed nodulocystic tumour (Figure 2). While predominantly seen within the lower dermis, extension into the subcutaneous tissue is not uncommon. The tumour is comprised of a basaloid proliferation resembling the hair matrix cells, which matures into structureless eosinophilic cells lacking nuclei called shadow cells (Figures 3 and 4). The shadow cell area represents differentiation towards the hair cortex. Frequently there are areas of calcification within the shadow cell regions (Figure 5). A histiocytic infiltrate with multinucleated cells forms at sites of rupture (Figure 6).
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