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Figure 3
Keywords: Squamous cell carcinoma in situ, Histopathology-image, Pathology
The scanning power view of squamous cell carcinoma in situ (SCCIS) reveals epidermal alteration (Figure 1). Closer inspection reveals atypia of the keratinocytes across the full thickness of the epidermis (Figures 2 and 3). There is a loss of the granular layer and overlying zones of parakeratosis. Sparing of the adnexal ostial epithelium is commonly seen (Figure 3). The keratinocytes show cytologic atypia with disorderly maturation.
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Source: dermnetnz.org