Pemphigus foliaceus pathology
Figure 2
Keywords: Pemphigus foliaceus, Histopathology-image, Pathology
Histology of pemphigus foliaceus
The low power view of the histology of pemphigus foliaceus is of a superficial epidermal blistering process. The low power clues include loss of the stratum corneum, increased prominence of the granular layer, or visible superficial epidermal separation with blister formation (Figure 1). At higher magnification subtle acanthloysis and spongiosis can be seen within the stratum granulosum, extending into the stratum corneum (Figures 2 and 3). This can form separation within the superficial epidermis, or as mentioned above, lead to complete loss of the stratum corneum. The prominent granular layer is seen as hyperchromasia of the nuclei within dyskeratotic cells in this layer, similar to the grains seen in Dariers disease (Figures 4 and 5).
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