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Merkel cell carcinoma pathology
Figure 3

Merkel cell carcinoma pathology

Figure 3  


Keywords: Merkel cell carcinoma, Histopathology-image, Pathology



Histology of Merkel cell carcinoma

Merkel cell carcinoma is a neuroendocrine carcinoma composed of densely blue cells. The tumour is centered in the dermis with frequent involvement of the overlying epidermis (figures 1, 2) and may invade the subcutaneous fat. The tumour forms sheets, nests and rarely ribbons. The outlines of the cells often mold together or resemble lymphocytes (figures 3, 4). There are numerous mitoses, and there may be necrosis. Lymphovascular invasion is common.

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Source: dermnetnz.org