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A positive Darier sign - rubbing an area of mastocytosis has resulted in redness, swelling, and urtication in 5 minutes
Extensive infantile mastocytosis - the yellow-orange colour and positive Darier sign is diagnostic
Mastocytosis in a baby - red-brown patches are characteristic. The left lower back lesion has urticated after rubbing - a positive Darier sign
Red-brown maculopapules typical of adult-onset urticaria pigmentosa (CM-patient1)
Red-brown papules of adult-onset urticaria pigmentosa on the abdomen (CM-patient1)
A solitary mastocytoma on the wrist - it will urticate if rubbed
Telangiectasia macularis eruptiva perstans - the lesions are more red in this variant of mastocytosis
Adult-onset urticaria pigmentosa - the lesions are more red than usual, and are often brown in colour (CM-patient2)
Adult-onset urticaria pigmentosa - the lesions are more red than usual, and are often brown in colour (CM-patient2)
Yellow-brown pigmented macules in juvenile mastocytosis
Juvenile mastocytosis: red-brown macular lesions on the trunk. They are likley to resolve over the next few years (CM-patient3)
Juvenile mastocytosis: red-brown macular lesions on the trunk. They are likely to resolve over the next few years (CM-patient3)
Juvenile mastocytosis: red-brown macular lesions on the neck. They are likely to resolve over the next few years (CM-patient3)
Juvenile mastocytosis: red-brown macular lesions on the neck. They are likely to resolve over the next few years (CM-patient3)
A solitary mastocytoma on an infant's chest
Red-brown monomorphic maculopapules in adult-onset urticaria pigmentosa
Red-brown monomorphic maculopapules in adult-onset urticaria pigmentosa
Lesions of infantile mastocytosis on the face and lids (CM-patient4)
Infantile mastocytosis - some lesions have blistered after urticating due to rubbing (CM-patient4)
Infantile mastocytosis - crusting is evident where blistering has been present (CM-patient4)
Infantile mastocytosis - crusting is evident where blistering has been present (CM-patient4)
Urticated plaques on the arm due to infantile mastocytosis (CM-patient4)
Red monomorphic maculopapules due to a variant of mastocytosis called telangiectasia macularis eruptiva perstans (CM-patient6)
Urticaria pigmentosa in an adult - dermoscopy showed telangiectasia; so called telangiectasia macularis eruptiva perstans (CM-patient6)
Red-brown maculopapules in adult onset urticaria pigmentosa
Diffuse cutaneous mastocytosis in an infant - the tan-orange colour is typical; blistering is more common in this variant
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