What is keratoelastoidosis marginalis?
Keratoelastoidosis marginalis presents as symmetric, hyperkeratotic, linear plaques along the lateral aspects of the hands. It has otherwise been reported as digital papular calcific elastosis of the hands, and degenerative collagenous plaques of the hands.
Histology of keratoelastoidosis marginalis
Histologic findings in keratoelastoidosis marginalis include epidermal acanthosis with some loss of the rete pattern associated with overlying hyperkeratosis (figure 1). There are thick acellular collagen bundles in the dermis (figure 2). In addition, there are fragmented degenerative elastic which may form elastotic masses. These masses sometimes calcify (figure 3).
Keratoelastoidosis marginalis pathology
Special studies for keratoelastoidosis marginalis
Elastic stains will show a reduction of elastic fibres. The residual elastic fibres are disorganised or can form masses
Differential diagnosis of keratoelastoidosis marginalis pathology
Dermal elastosis – the dense fibroplasia and clinical features help to distinguish this disorder from regular dermal elastosis.