Author: Adjunct A/Prof Patrick Emanuel, Dermatopathologist, Clinica Ricardo Palma, Lima, Peru. DermNet NZ Editor-in-chief: Adjunct A/Prof Amanda Oakley. July 2018.
Lymphangioma circumscriptum presents on the skin surface as grapelike groups of thin-walled, translucent, lymph-filled vesicles, often compared with frog spawn. Haemorrhage within the lesions can create a deep red or black appearance.
Histology of lymphangioma circumscriptum
In lymphangioma circumscriptum, histopathological examination reveals acanthosis and hyperkeratosis of epidermis (figure 1). Within the papillary and reticulardermis, there are dilated lymphatic channels containing eosinophilic proteinaceous material in the papillary dermis (figures 2,3).