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Cobblestone appearence of the gingivae in Cowden syndrome
Keywords: Cowden disease, Cowden syndrome, Anterior gingiva, Autosomal dominant genetic disorder, Cobblestone mucosal change, Mouth, Multiple hamartoma syndrome, Multiple white mucosal papules, Skin of colour
Cowden syndrome is a rare, autosomal dominant, inherited condition characterised by hamartomas in various organs, including breast, thyroid, uterus, brain, and mucocutaneous tissues with increased risk of malignancies. It is also known as ‘Cowden disease’ or ‘multiple hamartoma syndrome’.
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Source: dermnetnz.org