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Lax beetle dermatosis

Author: Ann L. Giles, Clinical Nurse Specialist, Greenlane Hospital, Auckland, New Zealand. DermNet NZ Editor in Chief: Adjunct A/Prof. Amanda Oakley, Dermatologist, Hamilton, New Zealand. Copy edited by Gus Mitchell. January 2020.


What is a lax beetle?

Lax beetles are common insects that are found worldwide, belonging to the family Oedemeridae [1–3]. The beetles are 6–20 mm long, soft-bodied, and slender. The body is a light brown colour with darker brown/black stripes or spots down the plate-like structure on the back [1,2].

Lax beetles are also called false blister beetles because the male beetles produce cantharidin, which is also found in the true blister beetles of the family Meloidae, to which they are closely related [1,3,4]. Meloidae beetles are not found in New Zealand. Cantharidin extracted from the beetle Cantharis vesicatoria is sometimes used to treat viral warts and molluscum contagiosum. ‘Kantharis’ means ‘blister fly’ in Greek [5].

The common names for the lax beetle include striped lax beetle, spotted lax beetle, false blister beetle, and pollen-feeding beetle.

Lax beetles

See more images of lax beetles.

Where are lax beetles found?

In New Zealand, most lax beetles are native with several adventive species, meaning they could have been introduced from other countries by humans [3]. The beetles are found in the North and South Islands of New Zealand, Stewart Island, and the Chatham Islands [2,3].

Beetles and young grubs are found on driftwood or rotting wood just above high tide in coastal areas and on vegetation inland. Adults are found under the bark of dead tree trunks and on tree branches. They feed on pollen and nectar from flowers or vegetation. On summer nights, adult beetles are attracted by and fly to bright artificial white lights [1–3].

Who gets blisters from the lax beetle?

Anyone can get blisters if the beetle is crushed, brushed or pressed against the skin when gardening or during outdoor activities. Sometimes called ‘morning blisters’, they occur hours after contact with the beetle [1,5,6].

Lax beetle blisters

What causes lax beetle dermatosis?

Crushing the beetle on the skin, or pressing or accidentally brushing against the skin, causes the beetle to release a fluid called haemolymph from its leg joints. The fluid contains cantharidin or cantharid, which is intended to deter predators from eating the beetle eggs and is irritating to human skin [1,3,7]. The male beetle passes the blistering fluid to the female beetle during mating [5].

The beetles do not bite or sting [8].

What are the clinical features of lax beetle dermatosis?

Blister beetle dermatosis is characterised by superficial blisters.

  • The face, neck, and chest are commonly affected.
  • Tense blisters filled with clear fluid develop 24–48 hours after contact with the blister beetle haemolymph.
  • Single or multiple vesicles, bullae, or multiple blisters appear in a line or track where the beetle has been in contact with the skin.
  • There may be mild itching and minimal surrounding erythema, but the blisters are not painful.
  • ‘Kissing or mirror-image’ lesions can be seen when a blister comes in contact with adjacent skin when bending the arms or legs [1,5,9].

What are the complications of lax beetle dermatosis?

There are no complications from blister beetle dermatosis, which heals within a few days without scarring [6,9].

How is lax beetle dermatosis diagnosed?

Lax beetle dermatosis is diagnosed from the clinical appearance and history of contact, or likely contact with a lax beetle.

What is the differential diagnosis for blister beetle dermatosis?

Other blistering conditions that may need to be considered include:

What is the treatment for blister beetle dermatosis?

Blister beetle dermatosis can be prevented by avoidance of contact with the beetle.

  • Screens will help to keep them outdoors.
  • Avoid touching the beetle.
  • If a beetle lands on the skin, blow it off rather than brushing or crushing it.

If blistering arises:

  • Wash the skin with soap and water or clean it with acetone or alcohol to dissolve and dilute the cantharidin.
  • Cover the area until the blister is absorbed to reduce the spread of cantharidin-containing fluid.
  • Symptomatic topical treatment may include the application of a mild topical steroid [1,7,8].

What is the outcome for lax beetle dermatosis?

The lax beetle blisters heal in 4–7 days without ulceration, infection, or scarring [6,9].



  1. Ghoneim KS. Human dermatosis caused by vesicating beetle products (Insecta), cantharidin and paederin: An overview. World Journal of Medicine and Medical Science 2013;1:01–26. Journal
  2. Paul LH. A systematic revision of the New Zealand Oedemeridae (Coleoptera, Insecta). J Royal Soc NZ. 1975;5(3):227-74. Journal
  3. Fauna of New Zealand, Ko te Aitanga Pēpeke o Aotearoa Number/Nama 37. Available at: [accessed 9 January 2020]
  4. Mehdinia A, Asiabi M, Jabbari A, Abtahi SM. Analysis of cantharidin in false blister beetles (Coleoptera: Oedemeridae) by headspace solid-phase microextraction and gas chromatography-mass spectrometry. J Chromatogr B Analyt Technol Biomed Life Sci. 2011 Oct 1;879(27):2897-901. doi: 10.1016/j.jchromb.2011.08.020. Epub 2011 Aug 22. PMID: 21907641. PubMed
  5. Aoun O, Francois, M, Demoncheaux, JP, Rapp C. Morning blisters: cantharidin-related Meloidae burns. J Travel Med. 2018 Jul 1;25(1). doi: 10.1093/jtm/tay045. PMID: 30016471. PubMed
  6. Nicholls DSH, Christmas TI, Greig DE. Oedemerid blister beetle dermatosis: a review. J Am Acad Dermatol. 1990 May;22(5 Pt 1):815-19. doi: 10.1016/0190-9622(90)70114-w. PMID: 2189910. PubMed
  7. Moed L, Scwayder TA, Chang, MW. Cantharidin revisited: a blistering defense of an ancient medicine. Arch Dermatol. 2001 Oct;137(10):1357-60. doi: 10.1001/archderm.137.10.1357. PMID: 11594862. PubMed
  8. Hegde SS, Bhat MR. An outbreak of blister beetle dermatitis in a residential school: a clinical profile. Muller J Med Sci Res. 2017;8:47–51. doi: 10.4103/0975-9727.199376. Journal
  9. Torbeck R, Pan M, de Moll E, Levitt J. Cantharidin: a comprehensive review of the clinical literature. Dermatol Online J. 2014 Jun 15;20(6):13030/qt45r512w0. PMID: 24945640. PubMed
  10. Christmas TI, Nicholls D, Holloway BA, Greig D. Blister beetle dermatosis in New Zealand. N Z Med J. 1987 Aug 26;100(830):515-17. PMID: 3330591. PubMed

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