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Marginal keratoderma
What is marginal keratoderma?
Marginal keratoderma is a form of papular palmoplantar keratoderma in which there are small firm warty or pearly papules on the sides of the hands and, in some cases, feet.
Marginal keratoderma
How is marginal keratoderma classified?
There are inherited and acquired forms of marginal keratoderma.
Inherited marginal keratoderma
The inherited form of marginal keratoderma is acrokeratoelastoidosis, which was first described by Costa in 1953; hence, it is sometimes called Costa acrokeratoelastoidosis. It affects both hands and feet.
Focal acral keratosis is a variant of acrokeratoelastoidosis.
Acquired marginal keratoderma
The acquired form of marginal keratoderma is often called keratoelastoidosis marginalis and is more common than acrokeratoelastoidosis.
Keratoelastoidosis marginalis is characterised by keratotic papules on the sides of the index fingers and thumbs in patients who have had a lot of exposure to the sun.
Further information about marginal keratodermas
See the DermNet pages on acrokeratoelastoidosis and keratoelastoidosis marginalis.
See smartphone apps to check your skin.
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References
- Zanini Maurício. Focal acral hyperkeratosis: case report and discussion on marginal keratodermas. An Bras Dermatol 2006; 81(Suppl 3): S293–6. DOI: 10.1590/S0365-05962006000900009. Journal
- Bhobe M, Tambe S, Jerajani H, Parulkar P. Keratoelastoidosis marginalis of the hands: A report in two farmers. Indian Dermatol Online J 2016; 7: 195–7. DOI: 10.4103/2229-5178.182364. PubMed Central
- Search: 'Acrokeratoelastoidosis'. OMIM, Online Mendelian Inheritance in Man. Available at: www.omim.org/search/?index=entry&sort=score+desc%2C+prefix_sort+desc&start=1&limit=10&search=Acrokeratoelastoidosis (accessed July 2018).
On DermNet NZ
- Acrokeratoelastoidosis
- Keratoelastoidosis marginalis
- Punctate-type palmoplantar keratoderma
- Keratoelastoidosis marginalis pathology
- Foot skin conditions
- Hand skin conditions
Other websites
- Acrokeratoelastoidosis — Medscape
- Palmoplantar keratoderma, punctate type III; PPKP3 — OMIM, Online Mendelian Inheritance in Man [entry 101850]
Books about skin diseases
See the DermNet NZ bookstore.