What is porokeratotic eccrine ostial and dermal duct naevus?
Porokeratotic Eccrine Ostial and Dermal Duct Naevus (PEODDN) is a rare congenital disorder of keratinisation. Keratinisation is the process by which the skin cells form in the epidermis. PEODDN is a special type of epidermal naevus.
Porokeratotic eccrine and hair follicle naevus is a very similar entity.
Porokeratotic eccrine ostial and dermal duct naevus
PEODDN is characterised by small discrete scaly papules arranged in a line, most commonly on the palm of the hand (or fingers) or or sole of the foot (or toes). It may extend onto the backs of the hands and feet. There are rare cases of extensive lesions affecting large parts of the body. PEODDN usually becomes more warty in appearance over time and nearly always persists despite treatment.
PEODDN is usually not associated with any symptoms, although, occasionally it can be a bit itchy.
What is the treatment for PEODDN?
Treatments aimed at reducing the thickness of the warty skin in the affected area include:
- Exfoliating agents (e.g creams containing salicylic acid, urea, propylene glycol)
- Topical retinoids (e.g tretinoin)
- Systemic retinoids (e.g acitretin)
These treatments are only partly effective.