DermNet provides Google Translate, a free machine translation service. Note that this may not provide an exact translation in all languages


Frontal fibrosing alopecia

Author: Dr Darshan Singh MBChB, Registrar, Department of Dermatology, Waikato Hospital, Hamilton, New Zealand, 2001. Updated by Adjunct A/Prof Amanda Oakley, Dermatologist, Waikato Hospital, Hamilton, New Zealand. May 2018. Revised and updated October 2020.


What is frontal fibrosing alopecia?

Frontal fibrosing alopecia is a patterned form of scarring hair loss along the frontal scalp hair margin. It was first described in a group of Australian women in 1994.

Who gets frontal fibrosing alopecia?

Although the typical patient with frontal fibrosing alopecia was described as a Caucasian post-menopausal woman over the age of 50, younger women, men, and children, and all ethnic groups including Asians, Hispanics, and those of African descent can be affected.

The incidence is reported to be increasing worldwide.

Frontal fibrosing alopecia is frequently reported in patients with hypothyroidism, contact allergy to fragrances, regular sunscreen use, and autoimmune diseases including lupus erythematosus and rheumatoid arthritis.

What is the cause of frontal fibrosing alopecia?

Genetic, hormonal, autoimmune, inflammatory, and environmental factors have postulated roles in the pathogenesis of frontal fibrosing alopecia. Pairs of monozygotic twins with frontal fibrosing alopecia and positive family histories reported in some cases suggest a genetic tendency. An androgen-dependent aetiology has been suggested by the predominance of post-menopausal patients. Contact allergy or photocontact allergy to cosmetics, moisturising creams, hair dye, and sunscreen have been suggested as possible but unconfirmed causative factors.

Frontal fibrosing alopecia has been considered a variant of lichen planopilaris due to the resemblance on histology and an association with various forms of lichen planus, but there are also many differences that raise doubts.

What are the clinical features of frontal fibrosing alopecia?

Frontal fibrosing alopecia usually presents as a uniform linear band of hair loss along the front and sides of the scalp hair margin, resulting in a receding frontal hair line. Atypical patterns of loss include a diffuse zig-zag pattern, a pseudo-fringe-sign, or continuous involvement all the way around the hair margin both front and back. 

The skin in the affected area lacks the sundamage seen on the forehead, allowing assessment of the extent of the recession. It looks pale, shiny, or mildly scarred, without visible hair follicle openings. During the active phase redness and scale is visible around involved hairs. Single 'lonely' hairs often persist in the bald areas. The hair pull test is negative.

Hair loss in frontal fibrosing alopecia is usually not restricted to the frontal hairline. Eyebrow thinning or loss (madarosis) often precedes the scalp changes. Hair loss can affect all parts of the body, and almost total loss from limbs is common. In men, loss of beard and sideburns is described and may be the only site of involvement.

Itch and pain are common early symptoms, and may occur before any obvious loss of hair density. Facial rashes are another potentially early sign. These may present as skin coloured or yellowish follicular papules located on the forehead and temples, diffuse erythema or red dots around hairs. 

Androgenetic alopecia (male pattern hair loss, female pattern hair loss) is commonly associated and may lead to missed diagnosis.

Frontal fibrosing alopecia

Madarosis in frontal fibrosing alopecia

What are the dermoscopy features of frontal fibrosing alopecia?

Dermoscopy reveals absent follicles, white dots, tubular perifollicular scale, and perifollicular erythema. In skin that tans easily, perifollicular pigmentation may be observed.

How do clinical features differ in various types of skin?

Women of African descent with frontal fibrosing alopecia present differently from Caucasian women. Typically they present at a younger age, often in their early 40s before menopause. Itch, redness, and scale are less obvious. Lichen planus pigmentosus is commonly associated, and usually precedes the hair loss. Speckled pigmentation of hair follicles along the frontal hair margin is seen on dermoscopy. Frontal fibrosing alopecia may be overlooked due to associated traction alopecia.

How is the diagnosis of frontal fibrosing alopecia made?

The clinical features of frontal fibrosing alopecia are characteristic.

Skin biopsy may be required to exclude other forms of scarring alopecia. The histopathological features of frontal fibrosing alopecia are identical to those of lichen planopilaris.

Biopsy of skin papules may also show a lichenoid pattern of inflammation, fibrosing alopecia, and sebaceous gland hyperplasia.

Diagnostic criteria have been proposed.

Major criteria:

  • Scarring hair loss of the frontal, frontotemporal, or temporal scalp in the absence of follicular keratotic papules on the body
  • Scarring loss of eyebrows.

Minor criteria: 

  • Redness and scale around hair follicles, or solitary 'lonely' hairs, best seen on dermoscopy
  • Characteristic histology on skin biopsy
  • Similar clinical signs involving other body sites
  • Noninflammatory facial papules
  • Itch or pain preceding or concurrently at sites of involvement.

Diagnosis requires two major criteria or one major and two minor criteria.

Recommended blood tests include haematology, biochemistry, thyroid function tests and ANA. Hormone status may assessed if there are other clinical features to suggest hyperandrogenism. Patch testing should be considered.

What is the differential diagnosis of frontal fibrosing alopecia? 

Androgenetic alopecia and traction alopecia often co-exist.

Other types of scarring hair loss need to be considered, but rarely share the band-like pattern of frontal fibrosing alopecia.

What is the treatment of frontal fibrosing alopecia?

There is no uniformly effective treatment for frontal fibrosing alopecia to date. A short course of oral steroids, intralesional steroid injections, anti-inflammatory antibiotics such as tetracyclines, or antimalarial tablets may benefit patients who have a rapid onset of hair loss. The 5-alpha-reductase inhibitors finasteride and dutasteride have been reported to stop further hair loss but this may be due to associated androgenetic alopecia. Immunosuppressants tried include ciclosporin and mycophenolate mofetil.

The use of the antidiabetic agent pioglitazone (off-label) for the treatment of frontal fibrosing alopecia was reported to reduce symptoms, inflammation, and progression of frontal fibrosing alopecia but its use has not been supported by further investigations. Side effects include ankle swelling and weight gain.

Rituximab and adalimumab are novel new treatments.

Hair grafting may be considered once disease activity has settled.

What is the outlook for frontal fibrosing alopecia?

Usually, frontal fibrosing alopecia is slowly progressive although it seems to be self-limiting in most cases after several years. The hair line recedes on average of 1.8-2.6 cm. As it is a scarring alopecia, hair does not regrow unless treatment is instituted early in the process.



  • Aldoori N, Dobson K, Holden CR, McDonagh AJ, Harries M, Messenger AG. Frontal fibrosing alopecia: possible association with leave-on facial skin care products and sunscreens; a questionnaire study. Br J Dermatol. 2016;175(4):762–7. doi:10.1111/bjd.14535. Journal.
  • Callender VD, Reid SD, Obayan O, Mcclellan L, Sperling L. Diagnostic clues to frontal fibrosing alopecia in patients of African descent. J Clin Aesthet Dermatol. 2016;9(4):45–51. PubMed
  • Ho A, Shapiro J. Medical therapy for frontal fibrosing alopecia: a review and clinical approach. J Am Acad Dermatol. 2019;81(2):568–80. doi:10.1016/j.jaad.2019.03.079. PubMed
  • Kossard S. Postmenopausal frontal fibrosing alopecia. Scarring alopecia in a pattern distribution [published correction appears in Arch Dermatol 1994 Nov;130(11):1407]. Arch Dermatol. 1994;130(6):770–4. Journal.
  • Kumaran MS, Razmi T M, Vinay K, Parsad D. Clinical, dermoscopic, and trichoscopic analysis of frontal fibrosing alopecia associated with acquired dermal macular hyperpigmentation: a cross sectional observational case-control study. J Am Acad Dermatol. 2018;79(3):588–91. doi:10.1016/j.jaad.2018.03.001. PubMed
  • Lis-Święty A, Brzezińska-Wcisło L. Frontal fibrosing alopecia: a disease that remains enigmatic. Adv Dermatol Allergol. 2020;37(4):482–9. doi:10.5114/ada.2020.98241. PubMed
  • Okereke UR, Simmons A, Callender VD. Current and emerging treatment strategies for hair loss in women of color. Int J Womens Dermatol. 2019;5(1):37–45. doi:10.1016/j.ijwd.2018.10.021. PubMed
  • Pirmez R, Barreto T, Duque-Estrada B, Quintella DC, Cuzzi T. Histopathology of facial papules in frontal fibrosing alopecia and therapeutic response to oral isotretinoin. J Am Acad Dermatol. 2018;78(2):e45. doi:10.1016/j.jaad.2017.10.038. Journal.
  • Tavakolpour S, Mahmoudi H, Abedini R, Kamyab Hesari K, Kiani A, Daneshpazhooh M. Frontal fibrosing alopecia: an update on the hypothesis of pathogenesis and treatment. Int J Womens Dermatol. 2019;5(2):116–23. doi:10.1016/j.ijwd.2018.11.003. PubMed
  • Valesky EM, Maier MD, Kaufmann R, Zöller N, Meissner M. Single-center analysis of patients with frontal fibrosing alopecia: evidence for hypothyroidism and a good quality of life. J Int Med Res. 2019;47(2):653–61. doi:10.1177/0300060518807335. PubMed

On DermNet

Other websites

Books about skin diseases


Related information

Sign up to the newsletter