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Granulomas are diagnosed when histopathology of a skin biopsy shows a granulomatous tissue pattern.
Granulomas may be found in the following skin conditions:
A granuloma is a chronic inflammatory pattern characterised by the localised aggregation of histiocytes with or without other inflammatory cells (eg plasma cells, eosinophils, neutrophils), with or without necrosis, with or without vasculitis, with or without calcification, with or without foreign bodies. They may be due to infection or chronic inflammatory disease or reactions to foreign material.
The dermatopathological features of various granulomatous disorders are described on the following pages:
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